Buy peptides South Africa

 

Myostatin

(GDF-8)

Go to | Back to Shop

 

Myostatin (GDF-8) is a member of the transforming growth factor-beta (TGF-beta) superfamily that is highly expressed in skeletal muscle, and myostatin loss-of-function leads to doubling of skeletal muscle mass. Myostatin-deficient mice have been used as a model for studying muscle-bone interactions, and here we review the skeletal phenotype associated with altered myostatin signaling. It is now known that myostatin is a key regulator of mesenchymal stem cell proliferation and differentiation, and mice lacking the myostatin gene show decreased body fat and a generalized increase in bone density and strength. The increase in bone density is observed in most anatomical regions, including the limbs, spine, and jaw, and myostatin inhibitors have been observed to significantly increase bone formation. Myostatin is also expressed in the early phases of fracture healing, and myostatin deficiency leads to increased fracture callus size and strength. Together, these data suggest that myostatin has direct effects on the proliferation and differentiation of osteoprogenitor cells, and that myostatin antagonists and inhibitors are likely to enhance both muscle mass and bone strength.

 

Go to | Back to Shop

Order and pay with credit or debit card here or use traditional order form here.
 
Share or Like this page :
    
 
Contact us - Email info@researchpeptides.co.za | Whatsapp : (060) 997 4604 | BBM Pin : PEPTIDES or D8DC1A4B
 
 
Please remember to read our disclaimer and consider it seriously. : View Disclaimer here,
Products sold for research purposes to registered establishments and persons.
Copyright Follistatin SA established 2006 - Copyright Research Peptides 2018 - Established 2013